- Resuscitation Outcomes and Clinical Characteristics of Out-of-Hospital Drug Induced Cardiac Arrest
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Yun Kwon Kim, Hyun Kim, Ho Kyong Won, Kwon Il Lee, Sung Bum Oh, Joong Bum Moon, Kang Hyun Lee, Sung Oh Hwang
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J Korean Soc Clin Toxicol. 2005;3(2):93-98. Published online December 31, 2005
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- Purpose: This study was to investigate the resuscitation outcomes and the clinical characteristics of non-traumatic drug-induced out-of-hospital cardiac arrest by analyzing data from a single institution's registry. Method: We conducted a retrospective study of 795 patients who came to the emergency department with non-traumatic drug-induced out-of-hospital cardiac arrest during the period $1991{~}2004$. Only patients over 18 years of age were included. Clinical characteristics. variables associated with cardiac arrest, and data during resuscitation were obtained from our cardiac arrest database. Patients were divided into two groups: drug-induced cardiac arrest (drug group, n=33), and non drug-induced cardiac arrest (non-drug group, n=762). Results: Spontaneous circulation was restored in 23 ($72{\%}$) patients in the drug group and in 314 ($45{\%}$) patients in the non-drug group ($x^2=0.020$). The patients who discharged alive number were 46 ($6{\%}$) in the non-drug group and 0 ($0{\%}$) in the drug group ($x^2=0.005$). The witnessed arrest, the epinephrine doses, and total defibrillation energy were not different between two groups. Conclusion: The return of spontaneous circulation rate was higher in the drug group than the non-drug group. However the drug group was lower survival discharge rate than in the non-drug group.
- A Case of Cantharidin Poisoning after the Ingestion of Herbal Medicine
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Ho Jin Ji, Hyun Kim, Sun Hyu Kim, Sung Bum Oh, Joong Bum Moon, Kang Hyun Lee, Sung Oh Hwang
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J Korean Soc Clin Toxicol. 2005;3(1):56-59. Published online June 30, 2005
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- Blister beetles produce cantharidin, which is toxic to people and animals. Cantharidin has been believed to be an aphrodisiac and an abortifacient based on its tendency to cause marked irritation to the genitourinary system leading to priapism in men and pelvic congestion in women for many years. Cantharidin was used by oriental traditional medicine for more than 2000 years. Typical signs related to cantharidin ingestion are gastrointestinal tract and urinary tract irritation, endotoxemia, shock and myocardial dysfunction. Cantharidin is a severe irritant to epithelial linings (gastrointestinal tract, urinary tract, and skin) and develop systemic inflammatory response syndrome. We report a case of corrosive esophagogastritis and acute renal failure by ingestion of cantharidin.
- Myopericarditis by an Ingestion of Hydrofluoric acid - A case report
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Sun Hyu Kim, Hyun Kim, Ho Jin Ji, Yong Soo Jang, Sung Bum Oh, Kang Hyun Lee, Sung Oh Hwang
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J Korean Soc Clin Toxicol. 2004;2(1):63-66. Published online June 30, 2004
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- Hydrofluoric acid (HF), one of the strongest inorganic acids, is used mainly for industrial purpose. Hydrofluoric acid injuries has a potential for both systemic as well as severe local tissue destruction. One of the most serious consequences of severe exposure to HF by any route is marked lowering of serum calcium (hypocalcemia) and other metabolic changes, such as hypomagnesemia and which may result in a fatal outcome if not recognized and treated. promptly cardiotoxicity is not well known except arrhythmias, which are a primary cause of death. We report a case of myopericarditis by ingestion of hydrofluoric acid.
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KSCT
Korean Society of Clinical Toxicology